Structured Reporting & Standardized Systems
The scoring and reporting frameworks that make nuclear medicine reproducible
Quick Answer
Standardized reporting turns subjective impressions into reproducible, comparable, and actionable statements — increasingly expected in nuclear medicine and essential for a reference platform. Each domain has its framework: Deauville/Lugano (lymphoma), PERCIST (metabolic response), PROMISE/PSMA-RADS (PSMA-PET), RECIP 1.0 (Lu-PSMA response), Krenning (SSTR), Perugini/H:CL (cardiac amyloid), IMPeTUs (myeloma), NI-RADS (head-and-neck post-treatment), and structured summed-score reporting for MPI.
Why it matters
- Reproducibility: two readers reach the same conclusion; serial studies are truly comparable.
- Actionability: each category maps to a management recommendation (e.g. NI-RADS levels, RECIP response classes).
- Communication & research: structured, coded data support registries, audit, AI, and — for a publishing platform — citable, comparable outputs.
The framework map
| Domain | System(s) |
|---|---|
| Lymphoma | Deauville 5-point · Lugano |
| Solid-tumor metabolic response | PERCIST (vs RECIST anatomic) |
| PSMA-PET | PROMISE (miTNM) · PSMA-RADS · RECIP 1.0 (therapy response) |
| Neuroendocrine (SSTR) | Krenning score |
| Cardiac amyloid | Perugini grade · H/CL ratio |
| Myeloma | IMPeTUs |
| Head & neck (post-treatment) | NI-RADS |
| Myocardial perfusion | 17-segment SSS/SRS/SDS, % myocardium, TID |
Minimum report elements (general)
Indication and relevant history; radiopharmaceutical, activity, and technique (uptake time, glucose, stress agent, attenuation correction); image quality/limitations; findings with the applicable standardized score; comparison to priors; and a clear, actionable impression.
Report the score, not just "positive/negative"
Standardized frameworks turn subjective impressions into reproducible, comparable, actionable statements — and each carries a management implication. Report the score (Deauville, PERCIST, PSMA-RADS, RECIP, Krenning, Perugini, IMPeTUs, NI-RADS, SSS/SRS/SDS), because "Deauville 4" or "NI-RADS 2" tells the clinician what to do next; "abnormal" does not.
Comparability is a discipline
Serial comparison is only valid when technique is held constant — same agent, uptake time, reconstruction/scanner, stress protocol, and reference region. This is why SUV needs harmonization (EARL) and why summed scores need a consistent software/normal database.
The minimum report
A complete report states the indication and history; the radiopharmaceutical, activity, and technique (uptake time, glucose, stress agent, attenuation correction); image quality/limitations; findings with the applicable standardized score; comparison to priors; and a clear, actionable impression. Structured, coded reporting is also the substrate for audit, registries, AI, and — for a publishing platform — citable, comparable outputs.
High-Yield Pearls
- Report the score, not just "positive/negative" — it carries the management implication.
- Hold technique constant for valid serial comparison (especially SUV/summed scores).
- Standardized, coded reporting is the substrate for audit, AI, and academic reuse.
Common Pitfalls
- Free-text impressions that omit the standardized category.
- Mixing frameworks or applying anatomic-only criteria (RECIST) where metabolic criteria (PERCIST/Deauville) are indicated.
Related Pages
- Reporting: Cardiac MPI reporting, Theranostics response criteria; physics: SUV harmonization & EARL.
Self-Check
Q1. Why report "Deauville 4" rather than "abnormal"?
Answer: The score carries a management implication — it tells the clinician what to do next; "abnormal" does not.
Q2. Match the framework to the domain: lymphoma, PSMA-PET response, neuroendocrine SSTR.
Answer: Lymphoma → Deauville/Lugano; PSMA-PET therapy response → RECIP 1.0 (with PROMISE/PSMA-RADS reporting); SSTR → Krenning score.
Q3. What makes serial comparison valid?
Answer: Holding technique constant — same agent, uptake time, reconstruction/scanner, stress protocol, and reference region (hence EARL harmonization and consistent normal databases).
Q4. When is it an error to apply RECIST (anatomic) criteria?
Answer: When metabolic criteria (PERCIST/Deauville) are indicated — anatomic-only criteria miss metabolic/molecular response.
Evidence & sources
https://nuc.med/structured-reporting/ Report an issue