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Deauville Score Helper

The 5-point lymphoma PET response scale, from lesion uptake vs reference regions

Evidence B#tool#oncology#lymphoma#response
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Select the most avid residual lesion's uptake relative to the reference regions (mediastinal blood pool and liver) to get the Deauville score and its usual interpretation. Context (interim vs end-of-treatment, trial setting) determines whether a score of 3 counts as a complete metabolic response — see Lymphoma.

Deauville score & response — computed from SUVs
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Deauville 5-point score
1 = no uptake · 2 = ≤ mediastinum · 3 = > mediastinum but ≤ liver · 4 = moderately > liver · 5 = markedly > liver (>~2×) and/or new lesions. Interim 1–3 is favourable; a Deauville 4 with a large interim ΔSUVmax (>66%) may still indicate response (per PET-adapted trials). At end-of-treatment, 1–3 = complete metabolic response, 4–5 = residual disease. Integrate with the full study and clinical context.

Evidence & sources

BDeauville 5-point scale — Barrington SF, et al. J Clin Oncol 2014; Lugano classification (Cheson 2014).
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