SUV Calculator

Body-weight standardized uptake value from activity concentration, dose, and weight

Evidence B#tool#oncology#PET#SUV

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The body-weight SUV normalizes a lesion's measured activity concentration to the injected dose and the patient's weight. It is a semiquantitative surrogate for metabolism — valid for comparison only when uptake time, glucose, scanner, and reconstruction are held constant (see FDG PET in Oncology).

SUV / SUL — decay & lean-body-mass corrected

Lesion activity concentration

kBq/mL

Injected activity (at injection)

MBq

Uptake time (inj → scan)

min

Isotope

Weight

Height

Sex

Blood glucose (optional)

mg/dL

SUVbw = conc(kBq/mL)×weight(kg)÷dose(MBq). SUL normalizes to lean body mass (Janmahasatian). Injected dose is decay-corrected to scan time. Optional glucose-corrected SUV (×glucose/100) is shown when entered. Keep uptake time, glucose and reconstruction constant for serial comparison; small lesions are underestimated (partial-volume).

PERCIST response (two time-points)

Baseline target SUL peak

Follow-up target SUL peak

Liver SUL mean (reference)

New lesion?

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change in SUL peak

PERCIST: a measurable target must exceed ~1.5×liver SUL mean + 2. CMR = below liver/background · PMR = ≥30% decrease · PMD = ≥30% increase or a new lesion · SMD = neither. Uses SUL peak, fixed liver reference, matched technique.

Evidence & sources

BEANM tumour-imaging guideline v2.0 (Boellaard) — SUV definition and standardization.